NASA Spaceline Current Awareness List #1,051 26 Could possibly 2023 (Space Life Science Investigation Final final results)

Space Biology on ISS

NASA

SPACELINE Current Awareness Lists are distributed by suggests of listserv and are out there on the NASA Activity Book internet website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. 

Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, [email protected].

Speak to for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an create-up that has not as well lengthy ago published or will publish in the upcoming weeks inside a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your create-up to the e-mail address described above. Articles received by Wednesday will appear inside that week’s list—articles received just right after Wednesday will appear the following week.

Papers deriving from NASA assistance:

1

Faerman A, Clark JB, Sutton JP.

Neuropsychological considerations for lengthy-duration deep spaceflight.

Front Physiol. 2023 Could possibly 1914:1146096. Critique.

https://doi.org/ten.3389/fphys.2023.1146096

Note: This create-up is portion of Investigation Topic “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior-Volume II” (https://www.frontiersin.org/investigation-subjects/47491/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview). The Investigation Topic also includes articles from earlier Current Awareness Lists #1,041 https://doi.org/ten.3389/fphys.2023.1141078 and #1,046 https://doi.org/ten.3389/fncir.2023.1135434. This create-up may possibly be obtained on the internet with out charge.

Journal Influence Aspect: 3.342

Funding: “Support from the Translational Investigation Institute for Space Properly becoming by suggests of NASA Cooperative Agreement NNX16AO69A is gratefully acknowledged. JS is supported by the Friedkin Chair for Investigation in Sensory Method Integration and Space Medicine at Baylor College of Medicine.”

two

Shelhamer M, Antonsen E, Reynolds R.

The have to have for a systems process in spaceflight effectively becoming and medicine.

2023 IEEE Aerospace Conference. 2023 Could possibly 15.

https://doi.org/ten.1109/aero55745.2023.10115773

PI: M. Shelhamer

Note: This create-up is a conference proceeding published by a peer-reviewed journal.

Journal Influence Aspect: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

3

Shelhamer M, Gersh JR.

A mission architecture to integrate human and spacecraft functional functionality.

2023 IEEE Aerospace Conference. 2023 Could possibly 15:1-eight.

https://doi.org/ten.1109/aero55745.2023.10115715

PI: M. Shelhamer

Note: This create-up is a conference proceeding published by a peer-reviewed journal.

Journal Influence Aspect: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

4

Hilditch CJ, Pradhan S, Costedoat G, Bathurst NG, Glaros Z, Gregory KB, Shattuck NL, Flynn-Evans EE.

Sex variations in perceptions of sleep inertia following nighttime awakenings.

Sleep Adv. 20234(1):zpac043.

https://pubmed.ncbi.nlm.nih.gov/37193286

Note: This create-up may possibly be obtained on the internet with out charge.

Journal Influence Aspect: Not out there for this journal

Funding: “This operate was supported in portion by the Naval Healthcare Investigation Center’s Naval Sophisticated Healthcare Improvement Method (MIPR N3239820WXHN007) and the National Aeronautics and Space Administration Airspace Operations and Safety Method, Method Wide Safety.”

5

Saint-Guillain M, Vanderdonckt J, Burny N, Pletser V, Vaquero T, Chien S, Karl A, Marquez J, Wain C, Comein A, Casla IS, Jacobs J, Meert J, Chamart C, Drouet S, Manon J.

Enabling astronaut self-scheduling creating use of a robust sophisticated modeling and scheduling strategy: An assessment all through a Mars analogue mission.

Adv Space Res. 2023 Apr 5. On the online ahead of print.

https://doi.org/ten.1016/j.asr.2023.03.045

Note: From the abstract: “Human lengthy duration exploration missions (LDEMs) raise a quantity of technological challenges. This paper addresses the query of the crew autonomy: as the distances enhance, the communication delays and constraints have a tendency to avert the astronauts from receiving monitored and supported by a actual time ground deal with.”

Journal Influence Aspect: 2.611

Funding: T. Vaquero and S. Chien are affiliated with NASA Jet Propulsion Laboratory. J. Marquez is affiliated with NASA Ames Investigation Center.

six

Schroeck H, Whitty MA, Martinez-Camblor P, Voicu S, Burian BK, Taenzer AH.

Anaesthesia clinicians’ perception of safety, workload, anxiousness, and strain in a remote hybrid suite compared with the operating space.

Br J Anaesth. 2023 Could possibly 16S0007-0912(23)00203-9. On the online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37202262

Journal Influence Aspect: 11.719

Funding: B.K. Burian is affiliated with NASA Ames Investigation Center.

7

Li M, Lee JD.

Modeling objective alignment in human-AI teaming: A dynamic game theory process.

Proc Hum Elements Ergon Soc Annu Meet. 2022 Oct66(1):1538-42.

https://doi.org/ten.1177/1071181322661047

PI: J.D. Lee

Note: This create-up is a meeting proceedings that published in peer-reviewed Sage journals. This create-up may possibly be obtained on the internet with out charge.

Journal Influence Aspect: 3.598

Funding: “This operate was supported by NASA Human Investigation Method No. 80NSSC19K0654.”

eight

Buettmann EG, Chlebek C, Lockard CA, Clayton SW, Lewis KJ, Collins KH.

Post or perish? Social media techniques for disseminating orthopedic investigation.

J Orthop Res. 2023 Could possibly ten. On the online ahead of print.

https://doi.org/ten.1002/jor.25588

PI: E.G. Buettmann

Note: This create-up may possibly be obtained on the internet with out charge.

Journal Influence Aspect: 3.103

Funding: “Dr. Evan Buettmann was supported by the Translational Investigation Institute for Space Properly becoming (TRISH) by suggests of Cooperative Agreement with NASA (NNX16AO69A). Dr. Kelsey Collins was supported by NIAMS (Grant K99AR078949).”

_______________________________________________________

Other papers of interest:

1

Almosa AS, Lockwood MB, Green SJ.

Effects of spaceflight on the human gastrointestinal tract microbiome.

J Indian Inst Sci. 2023 Could possibly 23. Critique.

https://doi.org/ten.1007/s41745-023-00384-7

Note: From the abstract: “In this short evaluation, we summarize the current state of understanding on the influence of space travel on the human gut microbiome, like investigation designs that involve animals (rodents), humans, and novel simulations. Experiments have been carried out under conditions of spaceflight, ground-mainly primarily based, and analogous flight simulation.”

two

Ejova A, Searston RA, Stephens R, Semmler C.

Clear pondering in deep space: A guide by cognitive scientists.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Tends to make use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. 31-47.

https://doi.org/ten.1007/978-981-19-9462-3_3

3

Oxlad M, Whitburn S, Carter AJ.

Optimizing mission final results: A holistic process to picking the best males and girls to travel to space.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Tends to make use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. 5-29.

https://doi.org/ten.1007/978-981-19-9462-3_two

4

Sakaki T, Koizumi T, Ikeido Y, Soga K, Wakabayashi K, Hoson T.

Improve in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls under hypergravity conditions.

Life Sci Space Res. 2023 Aug 2338:53-eight.

https://doi.org/ten.1016/j.lssr.2023.05.005

Note: A centrifuge was employed in this study.

5

Lv W, Peng X, Tu Y, Shi Y, Song G, Luo Q.

YAP [Yes-associated protein] inhibition alleviates simulated microgravity-induced mesenchymal stem cell senescence by suggests of targeting mitochondrial dysfunction.

Antioxidants. 2023 Apr 2312(5):990.

https://doi.org/ten.3390/antiox12050990

Note: A 2D clinostat was employed in this study. From the abstract: “Weightlessness in space leads to bone loss, muscle atrophy, and impaired immune defense in astronauts. Mesenchymal stem cells (MSCs) play critical roles in sustaining the homeostasis and function of the tissue. Even so, how microgravity impacts the traits MSCs and the connected roles in the pathophysiological alterations in astronauts keep barely identified.” This create-up is portion of Topic “Advances in Astrobiology” (https://www.mdpi.com/subjects/T9B7L6S956). This create-up may possibly be obtained on the internet with out charge.

six

Shamei A, Sóskuthy M, Stavness I, Gick B.

Postural adaptation to microgravity underlies fine motor impairment in astronauts’ speech.

Sci Rep. 2023 Could possibly 2213:8231.

https://pubmed.ncbi.nlm.nih.gov/37217497

Note: From the create-up: “The authors declare that the facts employed inside this evaluation was obtained from publicly out there sources, and all investigation was completed in accordance with human investigation ethics suggestions and regulations. The National Aeronautics and Space Administration (NASA) presents audio and video for a decision of missions by suggests of the public NASA photographs archive, which incorporates audio and video files of Astronaut interviews for selected missions. Audio files from each mission have been selected just simply because they function substantial speech facts (involving 70 and 120 s of speech) of astronauts proper away ahead of and just right after their respective missions, enabling direct comparisons of vowel space ahead of and just right after adaptations to microgravity. We evaluated vowel formants from four astronauts across four STS missions: (i) STS-129 (ii) STS-133, (iii) STS-134, and (iv) STS-135.” This create-up may possibly be obtained on the internet with out charge.

7

Yue Y, Yang J-Q, Lu S-Y, Ge J, Nie H-Y, Liu K-G, Liu F, Li H, Yan H-F, Zhang T, Sun P-M, Sun H-W, Yang J-W, Zhou J-L, Cui Y.

Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming improvement aspect-β1/Smad3 signaling pathway.

Skin Res Technol. 2023 Could possibly 829(5):e13341. On the online ahead of print.

https://doi.org/ten.1111/srt.13341

Note: A rotary cell culture strategy was employed in this study. This create-up may possibly be obtained on the internet with out charge.

eight

Zhang Y, Huang H, Yao C, Sun X, He Q, Choudharyc MI, Chen S, Liu X, Jiang N.

Fresh Gastrodia elata blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-connected pathways.

Front Pharmacol. 2023 Could possibly 314:1173920.

https://pubmed.ncbi.nlm.nih.gov/37205911

Note: Hindlimb unloading study. This create-up is portion of Investigation Topic “Exploring the Important Targets and Compounds That Manipulate Brain Neurocircuits Against Mental Troubles and Psychiatric” (https://www.frontiersin.org/investigation-subjects/44928/exploring-the-critical-targets-and-compounds-that-manipulate-brain-neurocircuits-against-mental-complications-and-psychiatric#overview). The Investigation Topic also includes an create-up from earlier Current Awareness List #1,050 https://doi.org/ten.3389/fphar.2023.1167398. Additional articles will be forthcoming and may possibly be found in the hyperlink to the Investigation Topic. This create-up may possibly be obtained on the internet with out charge.

9

Sim HJ, So HS, Poudel SB, Bhattarai G, Cho ES, Lee JC, Kook SH.

Osteoblastic Wls ablation protects mice from total physique irradiation-induced impairments in hematopoiesis and bone marrow microenvironment.

Aging Dis. 2023 Jun 114(3):919-36.

https://pubmed.ncbi.nlm.nih.gov/37191410

Note: This create-up may possibly be obtained on the internet with out charge.

ten

Zhang Q, Gerweck LE, Cascio E, Gu L, Yang Q, Dong X, Huang P, Bertolet A, Nesteruk KP, Sung W, McNamara AL, Schuemann J.

Absence of tissue-sparing effects in partial proton FLASH irradiation in murine intestine.

Cancers (Basel). 2023 Apr 1315(eight):2269.

https://pubmed.ncbi.nlm.nih.gov/37190197

Note: This create-up may possibly be obtained on the internet with out charge.

11

Waldbaum JDH, Xhumari J, Akinsuyi OS, Arjmandi B, Anton S, Roesch LFW.

Association involving dysbiosis in the gut microbiota of principal osteoporosis sufferers and bone loss.

Aging Dis. 2023 Apr 28. Critique.

https://pubmed.ncbi.nlm.nih.gov/37199579

Note: This create-up may possibly be obtained on the internet with out charge.

12

Badakva AM, Miller NV, Zobova LN.

Integration of vestibular, visual, and proprioceptive inputs in the cerebral cortex all through movement deal with.

Hum Physiol. 2023 Apr 2749(two):176-82. Critique.

https://doi.org/ten.1134/S0362119722600515

13

Kelly KR, Palombo LJ, Jensen AE, Bernards JR.

Efficacy of closed cell wet-suit at many depths and gas mixtures for thermoprotection all through military education dives.

Front Physiol. 2023 Could possibly 2414:1165196.

https://doi.org/ten.3389/fphys.2023.1165196

Note: This create-up may possibly be obtained on the internet with out charge.